I Gusti Made Reza Gunadi Ranuh, - and Alpha Fardah Athiyah, - and Andy Darma, - and Bony Pramono, - and Laksmi Suci Handini, - and Maria Christina Shanty, - and Subijanto Marto Sudarmo, - (2019) Effects of Heat-Killed Probiotic Complex on Acute Diarrhoea in Children. Carpathian Journal of Food Science and Technology, 11 (5). pp. 50-56. ISSN 20666845

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Abstract

Probiotics are known in paediatrics as a new alternative treatment for diarrhoea. Some studies have found that a heat-killed probiotic complex (HKPC) has the same potential effects as active probiotics on diarrhoea in children. However, there is little research on this subject. We conducted a study to examine the HKPC effect on duration of illness and degree of recovery from acute diarrhoea in 6–24-month-old children. This study is a randomised, double-blind, controlled clinical trial with children aged 6–24 months with acute diarrhoea. The children were divided into two groups: one received HKPC and the other placebo. Stool samples were collected prior to treatment to determine the presence of rotavirus and the evidence of fat and/or lactose malabsorption. All the children were observed regarding the duration of diarrhoea, stool frequency, and stool consistency until they recovered. A total of 98 children met the selection criteria. Rotavirus was found in more than half of the stool samples (53%). Fat malabsorption was present in 46% of the samples, yet lactose malabsorption was detected in only 8% of the samples. The HKPC group had a shorter recovery time (3 days) than the placebo group (4 days), which is not statistically different (p=0.100). There were no significant differences in recovery levels from the first day until the last day of observation (p=0.487). According to the result, administration of HKPC has no significant effect on duration of illness and level of recovery in 6–24-month-old children with acute diarrhoea.

Item Type:	Article
Uncontrolled Keywords:	Probiotics, Heat-killed probiotics, Duration of illness, Stool frequency, Stool consistency
Subjects:	R Medicine > R Medicine (General) R Medicine > RJ Pediatrics
Divisions:	01. Fakultas Kedokteran > Ilmu Kesehatan Anak (Sub Spesialis)
Creators:	Creators NIM I Gusti Made Reza Gunadi Ranuh, - NIDN8811010016 Alpha Fardah Athiyah, - NIDN0023087301 Andy Darma, - UNSPECIFIED Bony Pramono, - UNSPECIFIED Laksmi Suci Handini, - UNSPECIFIED Maria Christina Shanty, - UNSPECIFIED Subijanto Marto Sudarmo, - NIDN0010064803
Depositing User:	arys fk
Date Deposited:	13 Sep 2022 08:08
Last Modified:	28 Nov 2022 10:30
URI:	http://repository.unair.ac.id/id/eprint/117341
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