Leonardi Hadianto, - (2010) Konsentrasi Efektif Ekstrak Ocimum Basilicum Terhadap Juivilah Koloni Candida Albicans Pada Resin Akrilik. Skripsi thesis, UNIVERSITAS AIRLANGGA.

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Abstract

Background. Candida albicans is one of the etiology of denture stomatitis that colonize in the fitting surface of the dentures. Denture cleanser can be used to prevent the colonization of the Candida albicans. Ocimum basilicum extract has the eugenol inside linalool that can be used as an antifungal agent. Purpose. The aim of this study were loking for the effective concentration of Ocimum basilicurn to reduce numbers of colony Candida albicans. Method. This experimental laboratory study was using heat cured acrylic resin specimen without surface polishing with 10 x 10 x 1 mm in size. They were divided in 5 groups which are 5%, 7,5%, 10%, 12,5% of Ocimum basilicum extract and sterile aquadest was used for the control group. Each group consists of 7 specimens. All specimens were soaked in water for 48 hours, autoclave sterilized, soaked in sterile saliva for 1 hour and contaminated with Candida albicans solution for adherence evaluation. The data was analyzed using Anova Test and LSD. Results. There were significant difference number of colony Candida albicans in each group and the most effective concentration of Ocimum basilicurn extract for reducing the numbers of colony Candida albicans in the acrylic resin was 12,5%. Conclusion. Ocimum basilicum extract can reduce the numbers of colony Candida albicans.

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