Effects of different intensities of exercise on folliculogenesis in mice: Which is better?

Fita Kurnia Rahayu, - and Sri Ratna Dwiningsih, - and Ashon Saadi, - and Lilik Herawati, - (2021) Effects of different intensities of exercise on folliculogenesis in mice: Which is better? Clinical Experimental Reproductive Medicine, 48 (1). pp. 1-5. ISSN 22338233

[img] Text (Artikel)
Artikel 3.pdf

Download (510kB)
[img] Text (Similarity)
Similarity 3.pdf

Download (2MB)
[img] Text (Karil)
3.pdf

Download (295kB)
Official URL: https://ecerm.org/journal/view.php?doi=10.5653/cer...

Abstract

Objective Exercise is a risk factor for infertility in women. However, research on the effects of different intensities of exercise on folliculogenesis has not yielded clear results. This study was conducted to analyze the effects of differences in the intensity of exercise on folliculogenesis in mice. Methods Nineteen female BALB/c mice (age, 3–4 months; weight, 13–25 g) were randomly divided into four groups: control, mild exercise, moderate exercise, and high-intensity exercise. The mice in the exercise groups engaged in swimming, with additional loads of 3%, 6%, or 9% of body weight, respectively. There were five swimming sessions per week for 4 weeks, with a gradually increasing duration every week. At the end of the treatment, ovarian extraction was carried out and hematoxylin and eosin staining was performed to identify folliculogenesis. Results There were significant differences in the number of total follicles between the control and moderate-exercise groups (p=0.036) and between the mild- and moderate-exercise groups (p=0.005). The mean number of primary follicles was higher in the moderate-exercise group than in the mild-exercise group (p=0.006). The mean number of secondary, tertiary, and Graafian follicles did not differ significantly among groups (p≥0.05). However, the number of total follicles and follicles in each phase tended to increase after exercise, especially moderate-intensity exercise. Conclusion Exercise of different intensities affected the total number of follicles and primary follicles. The number of follicles of each phase tended to increase after exercise. Moderate-intensity exercise had better effects than other intensities of exercise.

Item Type: Article
Uncontrolled Keywords: Exercise, Health, Mice, Ovarian follicle
Subjects: R Medicine > R Medicine (General)
R Medicine > RG Gynecology and obstetrics
Divisions: 01. Fakultas Kedokteran > Obstetri Dan Ginekologi (Sub Spesialis)
Creators:
CreatorsNIM
Fita Kurnia Rahayu, -UNSPECIFIED
Sri Ratna Dwiningsih, -NIDN0028087307
Ashon Saadi, -NIDN8852800016
Lilik Herawati, -NIDN0014037509
Depositing User: arys fk
Date Deposited: 26 Dec 2022 01:37
Last Modified: 02 Feb 2023 03:17
URI: http://repository.unair.ac.id/id/eprint/119311
Sosial Share:

Actions (login required)

View Item View Item