Titiek Sunaryati (2010) Pengaruh Pemberian Ekstrak Umbi Bawang Putih (Allium Sativum Linn.) terhadap Jumlah Makrofag Pengekspresi NFKB, Sel Penghasil Interferon γ, dan Limfosit Penghasil Interleukin 2 pada Mencit BalB/C. Thesis thesis, UNIVERSITAS AIRLANGGA.

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Abstract

Common cold is an infectious disease that is caused by viruses. More than 200 hundreds viruses can cause this disease. Many people in this world have this disease. The purpose of this study is to explain how garlic extract can increase body immunity. This was experimental study using white male BALBI c strain mice, 10 weeks old with bodyweight of 25-35 grams. Group 1 received placebo (CMC Na) for 14 days. Group 2 received lOmg/kg BW garlic extract for 14 days, and group 3 received 20mg/kg BW garlic extract for 14 days. After 14 days mice were sacrified then intestines were removed and processed in the para:ffm block, then were stained with immunohistochemistry. There were three variables such as the amount of macrophage that expres NFKB, the amount of cell that produce interferon y, and the amount of lymphocyte that produce interleukin 2. Data were analyzed by analysis of variance Brown Forsythe, any significant different was further analyzed by using Games Howell in the significant level of 0.05. There were significant difference between groups those received placebo, 1 Omg/kgBw garlic extract, and 20mg/kgBw garlic extract in each variables. The conclusion of this experiment was garlic extract can increase body immunity via increase in the amount of macrophage that express NFKB, the amount of cell that produce interferon y, and the amount oflymphocyte that produce interleukin 2.

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