Efek Stimulasi Medan Elektromagnetik terhadap Penyembuhan Patah Tulang Tibia Tikus Putih (Rattus Norvegicus) Pascaovariektomi

Muhammad Nadlir Fakhry (2005) Efek Stimulasi Medan Elektromagnetik terhadap Penyembuhan Patah Tulang Tibia Tikus Putih (Rattus Norvegicus) Pascaovariektomi. Thesis thesis, UNIVERSITAS AIRLANGGA.

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Official URL: http://www.lib.unair.ac.id

Abstract

There were three indicators for fracture healing: the amount of osteoblast that express Transforming Growth Factor-13, the amount of osteoblat its self and the thickness of callus. Electromagnetic field stimulation was one of the alternative therapy to promote fracture healing in postmenopause, but the process remain unclear. Twenty Ratters norvergicus which have been underwent ovariectomized to have post menopause condition, one week afterward fracturized of the tibia was performed. These twenty rats then divided in two group, each contain 10 rats. First Group was control group which do not recieved electromagnetic field stimulation. Second group recieved electromagnetic stimulation for 6 hours a day for 4 week period. After 4 week all rats were underwent imunohistochemical and histopathological analysis for the amount of osteoblast that express Transforming Growth Factor-0, the amount of osteoblat its self and the thickness of callus. The number of osteblasts that express Transforming Growth Factor-0 in count per visual field were (0,78 ± 0,61 for r group and 2,75 ± 0,368 for 2nd ones) and the amount of osteoblat (4,88 ± 1,35 for 1st group and 12,62 ± 1,98 for 2nd ones), the 2nd group were significantly higher then the 1' ones. There was no significantly different in the Callus's thickness between the groups (166,5±15,99 for 1' group and 184,0± 57,63 for rd ones) . This experimental study shows that electromagnetic field stimulation can promote healing process in post ovarictomized fracture healing. These findings suggest that electromagnetic field stimulation can promote osteoporotic fracture healing in osteoporotic patients.

Item Type: Thesis (Thesis)
Additional Information: KKA KK TKD 09/06 Fak e
Uncontrolled Keywords: electromagnetic field stimulation, fracture healing, ovariectomy
Subjects: R Medicine > RB Pathology > RB37-56.5 Clinical pathology. Laboratory technique
Divisions: 01. Fakultas Kedokteran > Magister Ilmu Kedokteran Dasar
Creators:
CreatorsNIM
Muhammad Nadlir Fakhry090214759
Contributors:
ContributionNameNIDN / NIDK
Thesis advisorDjoko Roeshadi130325838
Thesis advisorPaulus Liben9900986841
Depositing User: Sulistiorini
Date Deposited: 17 Mar 2023 08:14
Last Modified: 17 Mar 2023 08:14
URI: http://repository.unair.ac.id/id/eprint/120656
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