Siti Farida (2001) Peranan Pentoksifilin In Vitro dalam Meningkatkan Motilitas Spermatozoa Manusia melalui Modulasi Spesies Oksigen Reaktif di Sperma : Penelitian Eksperimental Laboratorik. Thesis thesis, UNIVERSITAS AIRLANGGA.

Text (FULLTEXT) KKA KK TKR 06_01 Far p_FIX.pdf Download (2MB)

Abstract

All experimental laboratory study to see the influence of giving pentoxifylline in vitro to sperm motility with mechanism decreasing of concentrate of ROS on the semen was performed at Dr. Sutomo Hospital in Surabaya. Eight asthenozoospermic and eight normozoospermic semen samples. were exposed pentoxifylline in vitro with dose 3,6 mM. 7.2 mM and 10 mM incubated 370 C for thirty minutes. On asthenozoospermic group observed showing significant Increase of the percentage of sperm motility and semen ROS was significantly decreased (p < 0,01) on dose 3.2 mM; 7.2 mM and 10 mM. but on normozoospermic group significant on dose 7.2 mM and 10 mM (p≥0,05). In the dose 7,2 mM pentoxyfilline was optimal to decreased ROS and increased perccmage of sperm motility. Decreased of ROS would increased the percentage of spem motility.

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