MUHAMMAD RAMADHAN BRAHMANTYO, - and Intan Nirwana, - and Devi Rianti, - (2020) Application of Purple Leaf Extract (Graptophyllum Pictum) In Wound Healing Process of Collagen Density. International Journal of Pharmaceutical Research, 12 (4).
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Abstract
Background: Purple leaves are derived from the Graptophyllum pictum plant, the Acanthacea family contains: flavonoids, saponins, and tannins. Purple leaf extract has anti-inflammatory and analgesic effects. Purpose: This study observed an increase in the density of collagen in wounds in wistar rats. Methods: The research subjects were 24 adult and healthy Wistar (Rattus norvegicus) mice, aged 3 months, with a body weight of 200 grams, which were divided into 6 groups of 4 rats each. The making of purple leaf extract is as follows, purple leaf powder weighed as much as 500 grams, then moistened with 96% ethanol as much as 500 ml. Research data were analyzed using the Kruskall Wallis and Mann Whitney tests. Results: Statistical data analysis using the Kruskall Wallis test showed significant differences in collagen density (P<0.005). Conclusion: Giving a 15% purple leaf extract gel increases collagen density
| Item Type: | Article | ||||||||
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| Subjects: | R Medicine > RK Dentistry | ||||||||
| Divisions: | 02. Fakultas Kedokteran Gigi > Dental Material | ||||||||
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| Depositing User: | Muhammad Fadli Rois | ||||||||
| Date Deposited: | 28 Apr 2023 07:44 | ||||||||
| Last Modified: | 28 Apr 2023 07:44 | ||||||||
| URI: | http://repository.unair.ac.id/id/eprint/123936 | ||||||||
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