Rizka Musdalifah Amsar, - and Christofora Hanny Wijaya, - and Ika Dewi Ana, - and Atik Choirul Hidajah, - and Hari Basuki Notobroto, - and Triati Dewi Kencana Wungu, - and Anggraini Barlian, - (2021) Extracellular vesicles: a promising cell-free therapy for cartilage repair. Future science OA, 8 (2). ISSN 2506-5623

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Abstract

Few effective therapies for cartilage repair have been found as cartilage has a low regenerative capacity. Extracellular vesicles (EVs), including exosomes, are produced by cells and contain bioactive components such as nucleic acids, proteins, lipids and other metabolites that have potential for treating cartilage injuries. Challenges like the difficulty in standardizing targeted therapy have prevented EVs from being used frequently as a treatment option. In this review we present current studies, mechanisms and delivery strategies of EVs. Additionally, we describe the challenges and future directions of EVs as therapeutic agents for cartilage repair.

Item Type:	Article
Subjects:	R Medicine
Divisions:	10. Fakultas Kesehatan Masyarakat > Biostatistika dan Kependudukan
Creators:	Creators NIM Rizka Musdalifah Amsar, - - Christofora Hanny Wijaya, - - Ika Dewi Ana, - - Atik Choirul Hidajah, - NIDN0002116801 Hari Basuki Notobroto, - NIDN0025066504 Triati Dewi Kencana Wungu, - - Anggraini Barlian, - -
Depositing User:	Tn Chusnul Chuluq
Date Deposited:	27 Apr 2023 01:04
Last Modified:	27 Apr 2023 01:04
URI:	http://repository.unair.ac.id/id/eprint/124826
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