Comparison of IL-17 and FOXP3+ Levels in Maternal and Children Leprosy Patients in Endemic and Nonendemic Areas.

Flora Ramona Sigit Prakoeswa, - and Faradiba Maharani, - and Munawaroh Fitriah, - and Jusak Nugraha, - and Hardyanto Soebono, - and Budi Prasetyo, - and Santi Martini, - and Dominicus Husada, - and Hari Basuki Notobroto, - and Muhammad Yulianto Listiawan, - and Anang Endaryanto, - and Cita Rosita Sigit Prakoeswa, - (2021) Comparison of IL-17 and FOXP3+ Levels in Maternal and Children Leprosy Patients in Endemic and Nonendemic Areas. Interdisciplinary Perspectives on Infectious Diseases, 2021. pp. 1-7. ISSN 1687-7098

[img] Text (artikel)
C76_Artikel.pdf

Download (712kB)
[img] Text (turnitin)
C76_Turnitin.pdf

Download (1MB)
[img] Text (validasi)
C76_Validasi.pdf

Download (472kB)
[img] Text (turnitin)
Bukti Turnitin 19.pdf

Download (1MB)
[img] Text (validasi)
19 VALIDASI KADEP PER REVIEW.pdf

Download (935kB)
[img] Text (artikel)
19 Article all comparison.pdf

Download (800kB)
Official URL: https://www.hindawi.com/journals/ipid/

Abstract

Leprosy, a chronic infection caused by M. leprae, has a complex transmission problem that makes eradication programs difficult. New cases and ongoing transmission of leprosy in endemic areas make individuals living in endemic environments vulnerable to leprosy. This can be caused by the dysregulation of immune system in individuals living in leprosy-endemic areas. Although the number of male leprosy patients is higher, female leprosy patients have more impact on the family health status due to close contact with family members, roles in the household, and parenting. This could cause the increased number of children leprosy patients. We investigated the dysregulation of immune system by comparing IL-17 and FOXP3+ levels occurring in maternal and child leprosy patients in endemic and nonendemic areas. The results of the study found a statistically significant difference in IL-17 levels between the MB leprosy patient group and the control group (p=0.048), where higher levels of IL-17 are observed in the control group. A significant difference also was found in FOXP3+ levels between the group of healthy children living in endemic and those living in nonendemic areas (p=0.047), where higher FOXP3+ is observed in the healthy children living in endemic areas group.

Item Type: Article
Subjects: R Medicine
Divisions: 10. Fakultas Kesehatan Masyarakat > Biostatistika dan Kependudukan
Creators:
CreatorsNIM
Flora Ramona Sigit Prakoeswa, --
Faradiba Maharani, --
Munawaroh Fitriah, --
Jusak Nugraha, -NIDN0014025602
Hardyanto Soebono, --
Budi Prasetyo, -NIDN0003057605
Santi Martini, -NIDN0027096603
Dominicus Husada, -NIDN8800010016
Hari Basuki Notobroto, -NIDN0025066504
Muhammad Yulianto Listiawan, -NIDN8806800016
Anang Endaryanto, -NIDN8867700016
Cita Rosita Sigit Prakoeswa, -NIDN8865610016
Depositing User: Tn Chusnul Chuluq
Date Deposited: 27 Apr 2023 01:42
Last Modified: 27 Apr 2023 14:07
URI: http://repository.unair.ac.id/id/eprint/124847
Sosial Share:

Actions (login required)

View Item View Item