Astu Anindya Jati and Ummi Maimunah and Yuliasih and Iswan Abbas Nusi (2020) Fecal Calprotectin Associated with Spondyloarthritis Disease Activity. International Journal of Pharmaceutical Research, 12 (3). pp. 1414-1417. ISSN 0975-2366

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Abstract

Background: Fecal calprotectin (FC) is one of fecal biomarkers that has validation to distinguish the organic and functional bowel disease but the relationship with disease activity in Spondyloarthritis (SpA) is still questionable. We determined the correlation of FC to the degree of disease activity on SpA. Material and Method: This cross sectional analytic study involved thirty-two subjects diagnosed with SpA. FC levels were analyzed using ELISA method. The Spondyloarthritis disease activities were assessed by ASDAS- CRP scores. Results: The median age was 52.5 (23.0-71.0) years with the average ASDAS-CRP score of 2.53 ± 0.61. The median level of FC increased by 58.15 (5.20-269.20) μg/g and was found to be positive (≥50 μg/g) in 56.3% subjects. FC levels was significantly correlated with the degree of SpA activity according to ASDAS-CRP scores (r = 0.563; P = 0.001) Conclusion: Fecal Calprotectin associated with the degree of activity in the SpA measured by ASDAS-CRP scores.

Item Type:	Article
Uncontrolled Keywords:	Spondyloarthritis, Fecal Calprotectin, Disease activity, ASDAS-CRP
Subjects:	R Medicine > RC Internal medicine > RC31-1245 Internal medicine
Divisions:	01. Fakultas Kedokteran > Ilmu Penyakit Dalam
Creators:	Creators NIM Astu Anindya Jati NIM011218026311 Ummi Maimunah NIDN8896900016 Yuliasih NIDN8891010016 Iswan Abbas Nusi NIDN0028025003
Depositing User:	Ika Rudianto
Date Deposited:	28 Apr 2023 08:35
Last Modified:	28 Apr 2023 08:35
URI:	http://repository.unair.ac.id/id/eprint/125541
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