Natasya Ariesta Selyardi Putri and Ummi Maimunah and R. Haryanto Aswin and Izzatul Fithriyah and Muhammad Miftahussurur and Yoshio Yamaoka (2022) Quality of Life of Chronic Hepatitis B Patients Consuming Nucleoside Analog: A Case Control. Biomolecular and Health Science Journal, 5 (1). ISSN 2620-8636
![]() |
Text (Artikel)
20.Quality_of_Life.pdf Download (316kB) |
|
![]() |
Text (Karil)
20.karil_Quality_of-Live.pdf Download (418kB) |
|
![]() |
Text (Similarity)
20.similarity_Quality_of_Life.pdf Download (1MB) |
|
![]()
|
Image (Korespondensi)
20.Korespondensi.jpeg Download (54kB) | Preview |
Abstract
Introduction: Chronic hepatitis B raises serious concern due to its high morbidity, such as cirrhosis and hepatocellular carcinoma, and mortality from 267 per 100,000 person-years. Up to now, medical therapy that successfully eradicates the hepatitis B virus is not available. Therapy is given in the long term for suppressing viral replication and disease progression. Nucleoside analog (NA) is a medication that is consumed orally once a day for years. Previous studies showed that patients who were treated with NA had a different quality of life (QoL) compared to naïve patients. This research aimed to analyze the QoL of chronic hepatitis B patients who consumed NA by comparing it with naïve patients at Dr. Soetomo General Academic Hospital Surabaya. Methods: Subjects were recruited consecutively from chronic hepatitis B patients at Dr. Soetomo General Academic Hospital Surabaya during 9 February – 31 May 2021. Data about sociodemographic characteristics, hepatitis B therapy history, and QoL were gained by using the SF-36 questionnaire and medical records. Subjects were divided into NA and naïve groups which responses underwent an analytical comparison. Results: NA group had significantly higher QoL in a physical component score (PCS) and mental component score (MCS), with physical functioning (PF), role limitations due to physical health (RP), role limitations due to emotional problems (RM), energy/fatigue (VT), emotional well-being (MH), social functioning (SF), and general health perception (GH) subscales having p<0.05 Conclusion: The QoL of patients who were treated with NA was significantly higher than that of naïve patients in terms of physical and mental components.
Item Type: | Article | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Subjects: | R Medicine > RC Internal medicine > RC31-1245 Internal medicine | ||||||||||||||
Divisions: | 01. Fakultas Kedokteran > Ilmu Penyakit Dalam | ||||||||||||||
Creators: |
|
||||||||||||||
Depositing User: | Ika Rudianto | ||||||||||||||
Date Deposited: | 28 Apr 2023 15:38 | ||||||||||||||
Last Modified: | 28 Apr 2023 15:38 | ||||||||||||||
URI: | http://repository.unair.ac.id/id/eprint/125591 | ||||||||||||||
Sosial Share: | |||||||||||||||
Actions (login required)
![]() |
View Item |