Kun Arifi Abbas,, - and Nancy Margarita Rehatta, - and Yan Efrata Sembiring, - and Ghuraba Adisurya, - and Prananda Surya Airlangga, - and Hamzah, - and Hardiono, - and Bambang Pujo Semedi, - and Christijogo Sumartono Waluejo, - Acute kidney injury after a coronary artery bypass graft surgery. Bali Journal of Anesthesiology, 5 (3). ISSN 2549-2276

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Abstract

Abstract Background— Acute kidney injury (AKI) is a common complication after coronary artery bypass grafting (CABG) and is associated with adverse outcomes. However, the relationship between AKI after CABG and the long-term risk of end-stage renal disease (ESRD) is unknown. Methods and Results— This study included 29 330 patients who underwent primary isolated CABG in Sweden between 2000 and 2008. AKI was classified according to the Acute Kidney Injury Network (AKIN) classification: stage 1, >0.3 mg/dL (>26 μmol/L) or 50% to 100% increase; stage 2, 100% to 200% increase; and stage 3, >200% increase from the preoperative to postoperative serum creatinine level. Cox proportional hazards regression analysis was used to calculate hazard ratios with 95% confidence intervals for ESRD in AKIN stage 1 and stage 2 to 3. Postoperative AKI occurred in 13% of patients. During a mean follow-up of 4.3±2.4 years, 123 patients (0.4%) developed ESRD, including 50 (1.6%) in AKIN stage 1, 29 (5.2%) in AKIN stage 2 to 3, and 44 (0.2%) without AKI after CABG. After multivariable adjustment, the hazard ratio for ESRD was 2.92 (95% confidence interval, 1.87–4.55) for AKIN stage 1 and 3.81 (95% confidence interval, 2.14–6.79) for AKIN stage 2 to 3. Conclusions— This nationwide study of patients who underwent CABG found that a small increase in the postoperative serum creatinine level was associated with an almost 3-fold increase in the long-term risk of ESRD after adjustment for a number of confounders, including preoperative renal function

Item Type:	Article
Subjects:	R Medicine > R Medicine (General) > R5-920 Medicine (General)
Divisions:	01. Fakultas Kedokteran > Orthopaedi dan Traumatologi
Creators:	Creators NIM Kun Arifi Abbas,, - UNSPECIFIED Nancy Margarita Rehatta, - NIDN9990000073 Yan Efrata Sembiring, - NIDN0028017506 Ghuraba Adisurya, - UNSPECIFIED Prananda Surya Airlangga, - NIDN0023047608 Hamzah, - NIDN9900980405 Hardiono, - UNSPECIFIED Bambang Pujo Semedi, - NIDN0008027306 Christijogo Sumartono Waluejo, - UNSPECIFIED
Depositing User:	arys fk
Date Deposited:	29 Apr 2023 04:19
Last Modified:	29 Apr 2023 04:19
URI:	http://repository.unair.ac.id/id/eprint/125637
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