Voltammetric analysis of hydroquinone in skin whitening cosmetic using ferrocene modified carbon paste electrode

Muji Harsini*, .- and Untari Untari, .- and E. Fitriany, .- and A. N. Farida, .- and Mochamad Zakki Fahmi, .- and Satya Candra Wibawa Sakti, .- and Gustan Pari., .- (2019) Voltammetric analysis of hydroquinone in skin whitening cosmetic using ferrocene modified carbon paste electrode. Rasayan Journal of Chemistry, 12 (4). pp. 2296-2305. ISSN 0974-1496 ; 0976-0083

[img] Text (Fulltext)
C29. Fulltext_.pdf

Download (31MB)
[img] Text (Penilaian dan Validasi)
C29. Penilaian dan Validasi.pdf

Download (1MB)
[img] Text (Similarity)
C29. Similarity.pdf

Download (2MB)
Official URL: https://rasayanjournal.co.in/admin/php/upload/831_...


Hydroquinone is the most effective whitening agent in skin whitening cosmetics. It has the ability to whiten the skin in a relatively shorter time compared to other whitening agents. However, based on the regulations of the Indonesian Food and Drug Administration (BPOM) and the United States Food and Drug Administration (FDA), the use of hydroquinone in whitening cosmetics is prohibited and is given zero tolerance. Therefore, it is the aim of this study to develop an alternative method to analyze the presence of hydroquinone in cosmetics that is easier, inexpensive, selective, and accurate. The result showed that the best composition of the electrode membrane which gave the best outcome was carbon: paraffin: ferrocene with each ratio of 6 : 3: 1. The validity of the hydroquinone analysis method that uses carbon/ferrocene paste as the electrode shows good results with the working range of 0.20-10 µM, the sensitivity of 10.436 µA/µM, and detection limit of 0.06 µM. It is also selective in the analysis of a mixture of hydroquinone and arbutin. These electrodes have excellent accuracy in recovering hydroquinone analysis in cosmetic samples with an average recovery value of 99%. This electrode can also be used for arbutin analysis in cosmetics with an accuracy of 99%. This method is suitable to be used in skin whitening analysis, both hydroquinone and arbutin.

Item Type: Article
Uncontrolled Keywords: Hydroquinone, Arbutin, Voltammetry, Ferrocene, Cosmetics, Whitening Agent
Subjects: Q Science
Q Science > QD Chemistry
Q Science > QD Chemistry > QD450-801 Physical and theoretical chemistry
Divisions: 08. Fakultas Sains dan Teknologi > Kimia
Muji Harsini*, .-UNSPECIFIED
Untari Untari, .-UNSPECIFIED
E. Fitriany, .-UNSPECIFIED
Mochamad Zakki Fahmi, .-UNSPECIFIED
Satya Candra Wibawa Sakti, .-UNSPECIFIED
Gustan Pari., .-UNSPECIFIED
Depositing User: Mr Vega Andi Budiman
Date Deposited: 10 Jun 2023 05:50
Last Modified: 10 Jun 2023 05:50
URI: http://repository.unair.ac.id/id/eprint/125936
Sosial Share:

Actions (login required)

View Item View Item