Marissa Astari, - and Afif Nurul Hidayati, - and Medhi Denisa Alinda, - and Bagus Haryo Kusumaputra, - and Linda Astari, - and Muhammad Yulianto Listiawan, - and Indropo Agusni, - and Fedik Abdul Rantam, - and Sunarso Suyoso, - and Evy Ervianti, - and Yuri Widia, - and Sylvia Anggraeni, - and Cita Rosita Sigit Prakoeswa, - (2018) A Case Report: Role of Human Amniotic Membrane Mesenchymal Stem Cells-Conditioned Medium (hAMMSC-CM) Combine with Vitamin E for Treating Chronic Plantar Pedis Ulcer in Leprosy Patient. Proceedings of the 23rd Regional Conference of Dermatology, 1. pp. 493-495. ISSN 978-989-758-494-7

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Abstract

Leprosy ulcers are mostly present in plantar pedis especially in areas with bony prominance. Plantar ulcers healimg in leprosy ide often dificult and time comsuming because of the declining of growth factors and cytokines as a result of a prolonged inflammatory condition. A 70-years old man working as pedicab driver had an ulcer at his left feet since 2 yaers ago, painless and not itchy. On regio caput metatarsal digiti 1 pedis sinistra there were 4 x 4 x 0,4 cm with necrotic tissue around. The patient was suffering from borderline leprosy since 10 years and already finished the treatment without history of drop out. We applied topical human amniotic membrane mesenchymal stem cells-conditioned medium (hAMMSC-CM) combine with vitamin E gel for 5 weeks and the ulcer healed completely.

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