Karina Dyahtantri Pratiwi, - and Muhammad Yulianto Listiawan, - and Evy Ervianti, - and Cita Rosita Sigit Prakoeswa, - and Damayanti, - and Esti Hendradi, - and Sawitri, - (2021) The Efficacy of Topical Vitamin C and Microneedling for Photoaging. Berkala Ilmu Kesehatan Kulit dan Kelamin, 33 (1). pp. 55-62. ISSN 2549-4082

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Abstract

Background: Photoaging is premature skin aging caused by exposure to ultraviolet (UV) radiation. Vitamin C is an antioxidant that inhibits the tyrosinase enzyme that can reduce pigmentation. Microneedling procedure can improve the penetration of topical vitamin C, and it has skin rejuvenating effects to reduce wrinkles and minimize pore size. Purpose: The main purpose of this study was to evaluate the efficacy of topical vitamin C application after microneedling intervention for the clinical improvement of photoaging. Methods: Twenty-four women with photoaged skin participated in this randomization study, and they were divided into control and intervention groups. Solution of 0.9% NaCl and microneedling were performed to control group, and topical vitamin C and microneedling were performed to intervention group. Three intervention sessions were repeated at a 2 week interval. Signs of photoaging such as pigmentation, wrinkles, and pores were evaluated using Metis DBQ3-1, and the data were obtained numerically. Result: The data analysis revealed a significant improvement in pigmentation in the intervention group compared to control group (p<0.05). Wrinkles and pores evaluation revealed no significant difference between the control and intervention groups. Conclusion: Topical vitamin C after microneedling procedure has provided a significant improvement in pigmentation compared to NaCl 0.9% after microneedling.

Item Type:	Article
Uncontrolled Keywords:	photoaging, vitamin C, microneedling
Subjects:	R Medicine > R Medicine (General) R Medicine > RL Dermatology
Divisions:	01. Fakultas Kedokteran > Ilmu Kesehatan Kulit dan Kelamin (Spesialis)
Creators:	Creators NIM Karina Dyahtantri Pratiwi, - UNSPECIFIED Muhammad Yulianto Listiawan, - NIDN8806800016 Evy Ervianti, - NIDN8840900016 Cita Rosita Sigit Prakoeswa, - NIDN8865610016 Damayanti, - UNSPECIFIED Esti Hendradi, - NIDN0014115703 Sawitri, - NIDN8806900016
Depositing User:	arys fk
Date Deposited:	09 May 2023 01:31
Last Modified:	09 May 2023 01:31
URI:	http://repository.unair.ac.id/id/eprint/126429
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