Fatma Yasmin Mahdani, - and Diah Savitri Ernawati, - and Adiastuti Endah Parmadiati, - and Bagus Soebadi, - and Desiana Radithia, - and Yessy Andriani Fauziah, - and Nur Tsurayya Priambodo, - EFFECTIVENESS OF CITRUS LIMON PEEL ESSENTIAL OIL ON CANDIDA ALBICANS : IN VITRO STUDY. Biochemical and Cellular Archives, 20 (1). ISSN 0972-5075, 0976-1772

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Abstract

Candida albicans is a yeast that commensally inhabits the oral cavity might cause opportunistic infections and become pathogen in immunesupressed condition. More than 90% oral candidiasis caused by C. albicans infections. Citrus limon peel has active compound that may inhibits C. albicans growth. The purpose of this study is to investigate in vitro effectivness concentration of Citrus limon peel oil on C. albicans growth. Citrus limon peel essential oil that has obtained the serial dilution concentrations of 25%, 12.5%, 6.25%, 3.125%, 1.56%, 0.78%, 0.39% and 0.195% and added Candida albicans that had been grown in Sabouraud broth media. Furthermore, C.albicans grown on Sabouraud DextroseAgar and colonies were counted. MIC (Minimum Inhibitory Concentration) Citrus limon peel essential oil was 0.78%. MFC (Minimum Fungicidal Concentration) Citrus lemon peel essential oil 1.56%. Citrus limon peel essential oil with concentration 25%, 12.5%, 6.25%, 3.125% and 1.56% had in vitro effectiveness inhibiting and cause C. albicans death and Citrus limon peel esential oil with concentration 0.78% had in vitro effectiveness inhibiting C. albicans growth.

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