Muhammad Faizi, - and Nur Rochmah, - and Yuni Hisbiyah, - and Anang Endaryanto, - and Soetjipto, - (2021) Height for age in Children under 5 Years Old with Down Syndrome and Hypothyroidism. Indian Journal of Forensic Medicine & Toxicology, 16 (1). pp. 831-837. ISSN 0973-9130

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Abstract

Background: Children with Down syndrome tend to have accompanying comorbidities, such as hypothyroidism, and late detection of this ailment leads to reduced growth of the child. This study aimed to assess the growth patterns in children with Down Syndrome and hypothyroidism at diagnosis. Methods: This cross-sectional study was conducted from September to December 2020 with 56 subjects at the Pediatric Endocrine Outpatient Clinic of Dr. Soetomo Hospital. Diagnosis of Down Syndrome was confirmed by karyotyping, while the weights and heights were assessed using a standardized curve for children with Down Syndrome and then calculated using Peditools. Fifty-six children with Down Syndrome and hypothyroidism were included, comprising 32 boys and 24 girls (mean age, 37.75 ± 34.26 months). Majority of the subjects had normal weight, height, and Body Mass Index (36/56 [mean z-score, −1.62 ± 2.36], 33/56 [mean height-z-score, −0.43 ± 2.74], and 30/56 [mean z-score, −2.00 ± 2.06], respectively). Furthermore, the mean onset of diagnosis was 17.07 ± 32.23 months, where 23 out of the 56 children had short stature and had gotten diagnosed at over 12 months of age. Conclusion: From the results obtained, hypothyroidism can be said to be associated with reduced growth in children with DS.

Item Type:	Article
Uncontrolled Keywords:	down syndrome, growth, short stature, hypothyroidism
Subjects:	R Medicine > R Medicine (General) R Medicine > RJ Pediatrics
Divisions:	01. Fakultas Kedokteran > Ilmu Kesehatan Anak (Sub Spesialis)
Creators:	Creators NIM Muhammad Faizi, - NIDN8890900016 Nur Rochmah, - NIDN0029047909 Yuni Hisbiyah, - NIM011927017307 Anang Endaryanto, - NIDN8867700016 Soetjipto, - NIDN0017025004
Depositing User:	Mrs Elok Dian Nuraeni
Date Deposited:	30 May 2023 23:34
Last Modified:	30 May 2023 23:34
URI:	http://repository.unair.ac.id/id/eprint/126885
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• Height for age in Children under 5 Years Old with Down Syndrome and Hypothyroidism. (deposited 29 May 2023 23:03)
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