Alexander Tikara Sugondo and Djohar Nuswantoro, - and Paulus Budiono Notopuro and Deasy Ardiany (2019) Relationship between HbA1c Levels with eGFR and Blood Pressure in Type 2 Diabetes Mellitus Patients at General Hospital in Surabaya. Biomolecular and Health Science Journal, 2 (2). pp. 117-120. ISSN 2620-8636

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Abstract

Introduction: Diabetes mellitus is ranked seventh as the cause of death in the world, around 95% in the world is type 2 diabetes mellitus (T2DM). According to Riset Kesehatan Dasar (Riskesdas) in 2013, the prevalence of diabetes mellitus in Indonesia is 6,9%. Type 2 diabetes mellitus that is not well controlled will increase the risk of chronic complications, both microangiopathies such as nephropathy, and macroangiopathy such as hypertension. The aim of the study was to determine correlation between HbA1c levels with eGFR (Estimated Glomerulus Filtration Rate) and blood pressure (systolic and diastolic). Methods: An analytic observational cross-sectional study, collecting the data from 94 patients with T2DM,. The variables were collected from patient’s medical records. Analysis using Spearman’s Rank Correlation test. Results: From total 232 patients, 134 (57.8%) were females, 203 (87.5%) >45 years old with average age 55.57. There was no significant correlation between HbA1c and systolic blood pressure and there was no significant correlation between HbA1c and diastolic blood pressure.There was no significant correlation between HbA1c and systolic blood pressure (r=-0.127; p=0.054). Also no significant correlation between HbA1c and diastolic blood pressure (r=-0.111; p=0.093). Analysis on other factor showed a significant correlation between HbA1c and eGFR (r=0.341; p=0.000). Conclusion: No significant correlation between HbA1c and systolic blood pressure, and between HbA1c and diastolic blood pressure. Significant correlation between HbA1c and eGFR.

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