Optimal control of a mathematical model for Japanese encephalitis transmission

Heni Kharismawati, ,- and Fatmawati, ,- and Windarto, ,- Optimal control of a mathematical model for Japanese encephalitis transmission. In: Journal of Physics: Conference Series. IOP Science.

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Official URL: https://iopscience.iop.org/article/10.1088/1742-65...


Japanese encephalitis (JE) is a vector-borne disease that causes encephalitis mostly children in Asia and livestock. A mathematical model can be used to predict JE spread in the future. In this paper, we analysed a mathematical model of JE transmission. We also applied several optimal control variables such as vaccination and treatment to the human population, insecticide to mosquito population, and vaccination to pig population. Based on the analysis results, we obtained two equilibriums, namely disease-free equilibrium and endemic equilibrium. The existence and stability of the equilibriums depended on R0 (basic reproduction ratio). The disease-free equilibrium is locally asymptotically stable if R0 < 1, while the endemic equilibrium is locally asymptotically stable if R0 > 1. Furthermore, we determined the existence of the optimal control variables by Pontryagin Maximum Principle. Numerical simulation showed that the control strategies are effective to minimize the number of active JE in human, mosquito and pig population

Item Type: Book Section
Subjects: Q Science > QA Mathematics > QA1 Mathematics (General)
Q Science > QA Mathematics > QA297-299.4 Numerical Analysis
Q Science > QA Mathematics > QA370-387 Differential Equations
Divisions: 08. Fakultas Sains dan Teknologi > Matematika
Heni Kharismawati, ,-UNSPECIFIED
Fatmawati, ,-UNSPECIFIED
Depositing User: Mr Vega Andi Budiman
Date Deposited: 23 Jun 2023 23:53
Last Modified: 24 Jun 2023 09:31
URI: http://repository.unair.ac.id/id/eprint/127579
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