Diyantoro, Diyantoro and Aliyah Siti Sundari, Aliyah Siti Sundari and Rizka Oktarianti Ainun Jariah, Rizka Oktarianti Ainun Jariah and Dwi Wahyu Indriati, Dwi Wahyu Indriati and Dwi Wahyu Indriani, Dwi Wahyu Indriani (2022) A Potential Insect Antimicrobial of Black Soldier Fly Larvae (Hermetia illucens) against Pathogenic Bacteria. Research Journal of Pharmacy and Technology, 15 (10). pp. 4425-4433. ISSN 0974-360X

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Abstract

Antimicrobial activity of black soldier fly larvae extract against gram-positive and gram-negative pathogenic bacteria has been discovered. Water-soluble extracts have the most potential and effectiveness as antimicrobials, with MIC values ranging from 12.5 to 25 mg/mL for both gram-positive and gram-negative bacteria. BSF larvae also create peptides called defensins and cecropins, which have antibacterial properties. Defensins were the best and most effective peptides in inhibiting bacterial growth, inhibiting both gram-positive and gram-negative bacteria (MIC value = > 29.97 µM), while cecropins were more effective on gram-negative bacteria (MIC value= 0.52 – 2.07 µM) than gram-positive bacteria (MIC value not detected).

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