Kainat Rahman, - and Aryati, - and Ulfa Kholili, - and Bagus Setyoboedi, Bagus (2023) Profile of Liver Function Tests, Serology and Demographic Status of Children with Hepatitis B and Comorbidities at RSUD Dr. Soetomo in 2019 - May 2023. International Journal of Research Publications (IJRP.ORG), 129 (1). pp. 423-431. ISSN 2708-3578

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Abstract

Abstract Viral hepatitis is a global health problem. The risk of hepatitis B infection increases due to 95% transmission during pregnancy and 5% intra-uterine period. Infection in early life has a 90% risk of becoming chronic liver disease. There have not been many studies that suggest the profile of liver function test, serology and demographic status of children with hepatitis B diagnosis. This study aims to determine the profile of liver function test, serology and demographic status of children patients at RSUD Dr Soetomo Surabaya diagnosed with hepatitis B and comorbidities. This study used an operational descriptive method and total sampling technique of 21 child patients, 14 males (66.66%), 7 females (33.33%) and an average age of 9.7 years (9 months-17 years). Normality test results showed normal distribution of albumin (p=0.832), and abnormal bilirubin (p=0.004), total bilirubin (p=0.004), SGOT (p=0.000) and SGPT (p=0.000). Mean albumin was 3.58 g/dL (2.06-4.91), median SGOT 86 u/L (2-832), median SGPT 56 u/L (18-356), median total bilirubin 2.56 mg/dL (0.45-12.67) and median recruited bilirubin 1.54 mg/dL (0.10-9.94). SGOT and SGPT were found to be increased in 17 patients (80.95%) and 12 patients (57.14%) and albumin was found to be decreased in 7 patients (33.33%). Increased SGPT in 2 patients without comorbidities and 10 patients with comorbidities. decreased albumin was not found in pediatric patients without comorbidities and in pediatric patients with comorbidities found decreased albumin levels and increased levels of direc bilirubin and total bilirubin influenced by comorbidities at Dr. Soetomo Surabaya Hospital.

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