Sri Agus Sudjarwo and Widajat S (2006) Potensi Dan Mekanisme Kerja Isoflavonoid Untuk Proteksi Sel Endothelium Pada Hiperkolesterolemia. Other thesis, UNIVERSITAS AIRLANGGA.
![[img]](https://repository.unair.ac.id/style/images/fileicons/text.png) |
Text (fulltext)
sri agus sudjarwo20240201_14322515.pdf Download (2MB) |
Abstract
Protective effect of isoflavonoid on endothelial celi were studied in cholesterol-fed rabbits. The cholesterol-rich diet markedly increased Malondialdehyde (MDA) in the plasma as reflected by Thiobarbituric Acid-Reactive Substances (TBARS), decreased cGMP and decreased endothelium-dependent vascular relaxations to acetylcholine compared to vessels from normal rabbits. In cholesterol-fed rabbits, Isoflavonoid treatment decreased MDA in plasma production, increased cGMP and increased endothelium-dependent relaxations to acetylcholine. These results suggest that dietary treatment of rabbits with isoflavonoid may prevent superoxide anion (0.2) induced inactivation of endothelium-dependent relaxing factor (EDRF), improve the endothelium-dependent relaxation to acetylcholine in the aortic blood vessels and increase cyclic GMP content in aortic cholesterol-fed rabbits.
| Item Type: | Thesis (Other) | ||||||
|---|---|---|---|---|---|---|---|
| Subjects: | R Medicine > RC Internal medicine | ||||||
| Divisions: | 01. Fakultas Kedokteran > Ilmu Penyakit Mata | ||||||
| Creators: |
|
||||||
| Depositing User: | Diah Widjayanti | ||||||
| Date Deposited: | 20 Mar 2024 03:41 | ||||||
| Last Modified: | 20 Mar 2024 03:41 | ||||||
| URI: | http://repository.unair.ac.id/id/eprint/132101 | ||||||
| Sosial Share: | |||||||
Actions (login required)
 |
View Item |