THE EFFECT OF MUNG BEAN (Vigna radiata L.) SEED EXTRACT OINTMENT ON THE TOTAL NUMBER OF POLYMORFONUCLEAR NEUTROPHIL CELLS AND FIBROBLAS IN INCISIONAL WOUND HEALING ON ALBINO RATS (Rattus norvegicus)

DILIANA WAHYUNI ASIH, - (2022) THE EFFECT OF MUNG BEAN (Vigna radiata L.) SEED EXTRACT OINTMENT ON THE TOTAL NUMBER OF POLYMORFONUCLEAR NEUTROPHIL CELLS AND FIBROBLAS IN INCISIONAL WOUND HEALING ON ALBINO RATS (Rattus norvegicus). Skripsi thesis, UNIVERSITAS AIRLANGGA.

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Abstract

This study aimed to determine the effect of Mung Bean (Vigna radiata L.) Seed extract ointment was given topically on incisional wound healing on albino rats (Rattus norvegicus). Twenty-five male rats aged 3 months and 150-200 grams bodyweight were divided into 5 groups C-, C+, T1, T2, and T3. C- (rats with incisional wound treated with ointment base), C+ (rats with incisional wound treated with Povidone-iodine), T1 (rats with incisional wound treated with 5% MBSEO), T2 (rats with incisional wound treated with 10% MBSEO), and T3 (rats with incisional wound treated with 20% MBSEO). The Treatment was given topically twice a day for 14 days. On the 15th day, skin excisions were conducted, and histopathological examination was observed by the total number of polymorphonuclear neutrophil cells and fibroblast, then analyzed using the ANOVA test and followed by the Duncan test. The result of histopathological observations incision wound healing process to the number of polymorphonuclear neutrophil cells (PMN) and fibroblasts show that that there was a significant difference between C- (23.12c ± 2.58; 49.40b ± 2.82), C+ (11.08a ± 1.26; 39.88a ± 2.27), and treatment group T1 (18.56b ± 1.63; 67.84c ± 7.15), T2 (16.32b ± 2.65; 62.68c ± 2.68), T3 (9.32a ± 0.64; 35.72a ± 6.11). The result showed no significant difference (p>0.05) between T3 and C+. The conclusion of this study was Mung bean (Vigna radiata L.) seed extract ointment with a concentration of 20% has been proven to be effective to be used in incisional wound healing.

Item Type: Thesis (Skripsi)
Additional Information: KKC KK S.FKH. 115 - 23 Dil t
Uncontrolled Keywords: Mung bean (Vigna radiata L.), Polymorphonuclear Neutrophil Cells, Fibroblast, Wound Healing
Subjects: Q Science > QL Zoology > QL700-739.8 Mammals
Divisions: 06. Fakultas Kedokteran Hewan
Creators:
CreatorsNIM
DILIANA WAHYUNI ASIH, -NIM061811133055
Contributors:
ContributionNameNIDN / NIDK
Thesis advisorWIWIK MISACO YUNIARTI, -NIP196906011996032001
Thesis advisorMOHAMMAD SUKMANADI, -NIP196802031994031002
Depositing User: Dewi Puspita
Date Deposited: 25 May 2026 01:30
Last Modified: 25 May 2026 01:30
URI: http://repository.unair.ac.id/id/eprint/141439
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