Pengaruh Pemberian Ekstrak Umbi Porang (A. Oncopphyllus) Terhadap Histopatologi Arteri Koronaria Tikus Putih (Rattus Norvegicus) Yang Diinduksi Aloksan

Lilis Nur Aisyah, - (2022) Pengaruh Pemberian Ekstrak Umbi Porang (A. Oncopphyllus) Terhadap Histopatologi Arteri Koronaria Tikus Putih (Rattus Norvegicus) Yang Diinduksi Aloksan. Skripsi thesis, UNIVERSITAS AIRLANGGA.

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Abstract

"This study aims to determine the effect of giving porang tuber extract on the histopathology of the coronary arteries of white rats (Rattus norvegicus) induced by alloxan. The sample used was 30 white rats divided into six treatments, and five replications on each treatment. The following treatments were, K (-) (rats were only given 0.5 ml of alloxan aquades as a solvent and porang tuber extract solvent CMC Na); K (+) (rats were induced by alloxan 120 mg/kgBW/0.5 ml and administration of porang tuber extract solvent CMC Na); drug treatment (rats were induced by alloxan 120 mg/kgBW/0.5 ml and administration of metformin 45 mg/kgBW/0.5 ml once a day); P1 (rats were induced by alloxan 120 mg/kgBW/0.5 ml and administration of porang tuber extract at a dose of 100 mg/kgBW/0.5 ml once a day); P2 (rats were induced by alloxan 120 mg/kgBW/0.5 ml and administration of porang tuber extract at a dose of 200 mg/kgBW/0.5 ml once a day); P3 (rats were induced by alloxan 120 mg/kgBW/0.5 ml and administration of porang tuber extract dose of 400 mg/kgBW/0.5 ml once a day). The data were analyzed using Analysis of Variance (ANOVA) and if there were differences among the treatment, the data continued with Duncan Multiple Range Test of SPSS. The results showed there were a significant difference (p<0.05) on the thickness of the coronary artery walls of white rats (Rattus norvegicus). The conclusion showed that porang tuber extract (Amorphophallus oncopphyllus) can improve the histopathology of the coronary arteries wall thickness of white rats (Rattus norvegicus) induced by alloxan. "

Item Type: Thesis (Skripsi)
Additional Information: KKC KK S.FKH.51-22 Lil p
Uncontrolled Keywords: Amorphophallus oncopphyllus, Rattus norvegicus, histopathology of coronary arteries, alloxan
Subjects: S Agriculture > SF Animal culture > SF600-1100 Veterinary medicine
Divisions: 06. Fakultas Kedokteran Hewan
Creators:
CreatorsNIM
Lilis Nur Aisyah, -NIM061711133065
Contributors:
ContributionNameNIDN / NIDK
Thesis advisorYeni Dhamayanti, -NIDN0015036702
Thesis advisorROCHMAH KURNIJASANTI, -NIDN0019077004
Depositing User: sugiati
Date Deposited: 26 May 2026 03:22
Last Modified: 26 May 2026 03:22
URI: http://repository.unair.ac.id/id/eprint/141537
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