YUNIAR PUTRI S., 020911152 (2012) PEMBERIAN EKSTRAK BATANG POHON PISANG AMBON (Musa paradisiacal var. sapientum)UNTUK MEMPERCEPAT PROSES HEMOSTASIS PADA MENCIT (Mus muscullus). Skripsi thesis, UNIVERSITAS AIRLANGGA.

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Abstract

In dentistry, tooth extraction sometimes cause postoperative and perioperative complications especially in patients with bleeding disorder. Uncontrolled bleeding during tooth extraction may cause some effects such as hypovolemic shock, difficulty of wound healing and it becomesa port de entre of pathogenic bacteria that couldlead to an infection. The usingof local and systemic haemostatic may cause some side effects for the patients such as alveolar bone necrosis in the socket. Herb plants that can be used to accelerate bleedings, in the population of Trunyans, Bali, is the hump ofbananaambon. Musa paradisiaca var. sapientumhumpcontains several active compounds such as tannin and lectin. Tanin serves to incrase the secretion of ADP in the process of platelet agrregration whereas lectin can incrase secretion of von Wilebrand Factor (vWF) in the process of platelet adhesion on the injury vessels. Purpose: To know the influence of granting Musa paradisiaca var. sapientumhumpextract in concentrationof 25%, 50% and 100% againts haemostatic response on mice. Methods: A whole research sample divided into four groups. Group 1 is control, group of 2 was given 25% extract concentration, group of 3 was given 50% extract concentration and group of 4 was given 100% extract concentration of Musa paradisiaca var. sapientum humps. Then all the groups were examined their bleeding time and clotting time. Results: A group with 100% extract of Musa paradisiaca var. sapientum hump having the shortest bleeding time and clotting time. Conclusion: Musa paradisiaca var. sapientum hump extract with concentration of 25%, 50% and 100% could expedite bleeding and clotting time on mice.

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