LIA LISTIANI ROGA, 021211131017 (2016) Efektifitas Ekstrak Kulit Buah Nanas (Ananas comosus (L) Merr.) sebagai Desinfektan Resin Akrilik untuk menghambat pertumbuhan Candida albicans. Skripsi thesis, UNIVERSITAS AIRLANGGA.

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Abstract

Background: Pineapple peel extracts contains active compound among others, enzym bromelin, flavonoids, saponins, and tanins have anti-fungal. Acrylic resin is the most common material used for removable denture base. However, the character of porous in acrylic resin can possibly become a place for Candida albicans. As a result, this condition can increase the number of C.albicans in oral cavity, one of which is Candida albicans. C.albicans even can grow rapidly in dentures with poor oral hygiene. Objective: To determine effectivenes of pineapple peel extracts as desinfection on acrylic resin for inhibiting the formation of fungus candida albicans. Materials and Methods: First for the treatment groups acrylic plates that had been contaminated with C.albicans were soaked in pineapple peel extracts with a concentration 6,25%,12,5%,25%. Meanwhile, for control group the plate was soeked in sterile distilled water. Next, after the acrylic plates were placed over a vibrator to loss fungal colonies, spreading was conducted on Sabboroud Dextrose Agar to count the member of C.albicans manually with colony forming unit (cfu/ml). Result: Significant difference among those treatment groups. It is known from the value of p<0.05. Conclusion: The most concentration of pineapple peel extract can inhibits the growth of C.albicans is 25%.

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