Uji In Vitro Dan In Silico Carboxymethyl-Chitosan (Cmchi)-Benzaldehid Terhadap Bakteri Escherichia Coli

Bintang Pamungkas Syamon (2015) Uji In Vitro Dan In Silico Carboxymethyl-Chitosan (Cmchi)-Benzaldehid Terhadap Bakteri Escherichia Coli. Skripsi thesis, UNIVERSITAS AIRLANGGA.

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Official URL: http://lib.unair.ac.id

Abstract

Carboxymethyl-chitosan (CMChi)-Benzaldehid disintesis sebagai agen bakteri terhadap Escherichia coli. Aktivitas antibakteri ditentukan dengan metode Cakram Disc Diffusion dan pengukuran zona hambat di sekitar kertas cakram. Aktivitas antibakteri CMChi dan CMChi-benzaldehid diuji pada variasi konsentrasi 2%, 4%, 6%, 8%, dan 10%. Konsentrasi optimum CMChi dan CMChi-benzaldehid dalam menghambat pertumbuhan Escherichia coli sebesar 4% dan 6% secara berturut. Hasil zona hambat (diameter) yang dilakukan secara duplo didapatkan sebesar 3 dan 4mm pada CMChi 4% serta 6 dan 9mm pada CMChi-benzaldehid 6%. Energy binding yang dihasilkan CMChi dan CMChi-benzaldehid berturut-turut didapatkan dengan uji Molekular Docking pada protein FhuA membran outer Escherichia coli dengan nilai sebesar -2,99 kkal/mol dan -4,71 kkal/mol.

Item Type: Thesis (Skripsi)
Additional Information: KKC KK MPK 37/15 Syo u
Uncontrolled Keywords: BAKTERI Escherichia coli
Subjects: Q Science > QD Chemistry > QD71-142 Analytical chemistry
Divisions: 08. Fakultas Sains dan Teknologi > Kimia
Creators:
CreatorsNIM
Bintang Pamungkas SyamonNIM081115036
Contributors:
ContributionNameNIDN / NIDK
Thesis advisorH. Suyanto,, Dr. Ir., M.SiNIDN-
Depositing User: prasetyo adi nugroho
Date Deposited: 19 Nov 2015 12:00
Last Modified: 23 Mar 2020 03:31
URI: http://repository.unair.ac.id/id/eprint/28303
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