SUSY KRISTIANI (2013) PEWARISAN KARAKTERISTIK METRIS DAN NON METRIS GIGI (STUDI PADA POPULASI TENGGER). Disertasi thesis, UNIVERSITAS AIRLANGGA.

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Abstract

Background: Genetic basis of a trait can often be analyzed by making a reliable family history (pedigree). Genetic factors are often doubted as the cause of a heritable trait, particularly in multifactorial inheritance. Therefore, research needs to be done to prove that the inheritance actually involves genetic factors. This research studied the inheritance pattern that underlies dental characteristics inheritance in a population. Tengger region is historically a closed area, and has a tradition of endogamy marriages. Thus, Tengger has relatively homogeneous population. Therefore, it is assumed that there is a strong relationship between generations on dental characteristics in three generations of one family. Objective: On Research dental characteristics inheritance in Tengger population and Javanese population in Surabaya as comparison was performed to prove the strength of relationship between second and third generation on: l) dental metric characteristics, and 2) dental non-metric characteristics, as well as to prove the contribution of genetic and environmental factors. Material and method: The study was conducted to two generations of one family in Tengger population and Javanese population in Surabaya by measuring dental metric characteristic, i.e. mesiodistal size, labiolingual size of permanent maxillary first incisors, mesiodistal size, buccolingual size of the permanent maxillary first molar, mesiodistal-labiolingual index calculation, mesiodistal-buccolingual index, as well as observing dental non-metric characteristics, i.e. shovel shape of first permanent maxillary incisors and Carabelli s cusp of permanent maxillary first molar. Dental characteristics were measured and observed in study models. Results: The results of the study are as follows: 1) Mesiodistal size of the first permanent maxillary incisor was inherited from father and mother to son and daughters (r = 0.415; p = 0.001), from father to son and daughter (r = 0.504; p = 0.017), from mother to son and daughter (r = 0.339; p = 0.043), from father to son (r = 0.639; p = 0.019) and from mother to son (r = 0.471; p = 0.036) in Tengger population ; 2) Carabelli s cusp of maxillary first permanent molar was inherited from father and mother to son and daughter (r = 0.305; p = 0.026), from father to son and daughter (r = 0.560; p = 0.007)), from father to son (r = 0.711; p = 0.007) and from mother to daughter (r = 0.575; p = 0.040) in Tengger population, as well as from father and mother to son and daughter (r = 0.472; p = 0.004) of Java populations in Surabaya; 3) Mesiodistal size of permanent maxillary first molar was inherited from father and mother to son and daughter (r = 0.349; p = 0.012), from father to son and daughter (r = 0.828; p = 0.000), from father to son (r = 0.804; p = 0.001), and from father to daughter (r = 0.917; p = 0.004) in Tengger population; 4) Shovel shape of first permanent maxillary incisor was inherited from father and mother to son and daughter (r = 0.262;p = 0.047) and from father to son and daughter (r = 0.426; p = 0.048) in Tengger population; 5) Mesiodistal-labiolingual index was inherited from mother to son and daughter (r = 0.414; p = 0.012) and from mother to son (r = 0.563; p = 0.010) in Tengger population ; 6) Labiolingual size of first permanent maxillary incisors was inherited or there is a negative relationship from mother to daughter (r = -0.530; p = 0.042) in Tengger population. Conclusion: The conclusion of this study is that in relatively homogeneous population metric and non-metric dental characteristics are passed down from parents to their children with a particular pattern. When the dental characteristics are examined at a relatively heterogeneous population, Carabelli s cusp still has a significant relationship between parents and children. This may imply that the genetic factor of Carabelli s cusp inheritance is very prominent.

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