Inne Arianne Gobel (2015) Pengaruh Paparan Debu Kapur Terhadap Penurunan Faal Paru Dan Peningkatan Kadar IL-6 Serum Darah Pada Pekerja Pengalah Batu Kapur Di Desa Kesamben Kecamatan Plumpang Kabupaten Tuban. Thesis thesis, UNIVERSITAS AIRLANGGA.

Preview	Text (ABSTRAK) gdlhub-gdl-s2-2015-gobelinnea-39413-7.summa-y.pdf Download (637kB) | Preview
	Text (FULLTEXT) Binder1.pdf Restricted to Registered users only Download (2MB) | Request a copy

Abstract

Limestone produces silica dust long time exposure with dust exposure size as big as 3-5 mg / m3 can cause inflammatory reactions due to increase of IL-6 serum level and decline in lung function. The approach used in this research was a cross sectional. Measurement of lung function and IL-6 level of serum performed after they worked (case group) and health center officers (control group). The total sample was 18 respondents divided into 9 sample case group that works in the processing of limestone and 9 samples of the control group who work in health centers. The sample was taken randomly and based on the inclusion criteria. The measurements used PDS for limestone dust exposure, lung function measurement (FVC and FEV1) used a spirometer (Spirolab III), and measurement of IL-6 levels of blood serum used ELISA technique. Characteristics of respondents include, age and length of work. The results of regression test analysis showed that limestone dust exposure significantly affected the increase in IL-6 levels of serum (p <0.05) but not for the decline in lung function. Physical activity and the immune system of each individual were a factor that could affect the respiratory symptoms due to increased levels of IL-6 serum so the decrease of lung function after working 6 was not happened. The use of self protective equipment such as Air Purifying Respirator Non-power types (NAPR) is important to prevent ingress of dust resulting from the processing of limestone. Moreover, required the great attention of local governments and health department to provide medical check up periodically and regularly to monitor the condition of physical health of industry workers and see the diseases that often occur each year mainly related with IL-6 levels of serum.

Actions (login required)

View Item