SRI RAHAYU, 090515582M (2007) PENGARUH PEMBERIAN ROYAL JELLY TERHADAP GAMBARAN HISTOLOGIS OVARIUM TIKUS PUTIH (Rattus norvegicus) PENELITIAN EKSPERIMENTAL LABORATORIK. Thesis thesis, UNIVERSITAS AIRLANGGA.

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Abstract

The aim of this research was to study the Influence of Royal jelly that given per oral in a few dose to estimate histology of white mouse (Rattus norvegicus) ovary, covering the amount of primary follicle, secondary follicle, tertiary follicle and de Graaf follicle. This research pertained in research of laboratory's experiment, used randomized Complete design with experiment group and control group of 28 white mouses (Rattus norvegicus) divided at random become 4 groups, each group consist of 7 white mouses. Control group given by 0.5 % CMC, 2 ml/200g Body Weigh (BW) per oral by sonde. Royal jelly Treatment group of dose 12.5 mg/200g BW/day, given by 0,625% solution, 2 ml/200g BW/day. Royal jelly Treatment group of dose 25 mg/200g BW/day, given by 0,125% solution, 2 ml/200g BW/day. Royal jelly Treatment group of dose 37.5 mg/200g BW/day, given by 1,875 solution, 2 ml/200g BW/day. The treatment was given once of a day, executed during 4 white mouse lechery cycle or 16 day. Result of different test with one way manner analysis obtained by result of primary follicle, tertiary follicle and follicle of de Graaf have value of p > 0,05 and secondary follicle have value of p < 0,05 that was equal to 0,049. The least significant difference test showed difference between control group and Royal jelly treatment group of dose 37,5 mg/200g BW/day with value of p equal to 0.041, treatment group of dose 12,5 mg/200g BW/day and treatment group of dose 37,5 mg/200g BW/day with value of p equal to 0.046, treatment group of dose 25 mg / 200g BW/day and treatment group of dose 37,5 mg / 200g BW/day with value of p equal to 0,007. Correlation test using Pearson correlation test with a 0,05 got value of p equal to 0,146 for dose 12,5 mg, 0.832 for dose 25 mg and 0.667 for dose 37,5 mg, according to this result concluded that there are no significant relation between the dose of Royal jelly. Thereby, the Royal jelly's giving with various dose can improve amount of secondary follicle but do not show amount improvement of primary follicle, tertiary follicle and de Graaf follicle to white mouse (Rattus norvegicus) ovary. At correlation test there were no correlation of Royal jelly's giving with various dose to growth improvement of white mouse (Rattus norvegicus) ovary follicle.

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