IRFIANSYAH IRWADI, NIM010941010 (2011) PERBEDAAN PENGARUH LATIHAN FISIK SUBMAKSIMAL ANTARA PAGI DAN SORE HARI TERHADAP KADAR ASAM URAT DARAH PENELITIAN EKSPERIMENTAL LABORATORIS. Thesis thesis, UNIVERSITAS AIRLANGGA.

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Abstract

Hyperuricemia causesmany problems in the community. It has been known that exercise can leads to increased blood uric acid levels. The hormone cortisol is also increased during exercise. This hormone can increaseprotein degradationin muscle, which may be a substrates for purines metabolism andended as uric acid. This hormone also have a circadian rhytm, which is the peak levelwas obtained in the morning, and declined in the evening. The purpose of this study is to compare the increasing of blood uric acid levels after submaximal exercise between morning exercise and evening exercise. A total of eight subjects were treated in the form of submaximal physical exercise by pedaling ergocycle. The treatment repeated two times, in the morning and evening with a two daysdistance. Blood samples were taken before and after the exercise. Paired t test showed significantly increasing (tcount< ttable) of blood uric acid levels in the morning (from 6.188 mg/dL to 7.100 mg/dL) and in the evening(from 6.4 mg/dL to 7.538 mg/dL). Independent T-test showedthere was no significant difference (t count > t table) between the increase in blood uric acid levels after submaximal exercise in the morning compared with evening.The conclusion wasthat submaximal physical exercise in the morning and in the evening have the same risk of increasing blood uric acid level.

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