Nurmawati Fatimah, NIM011041014 (2012) EFEK FARMAKOLOGI EKSTRAK ETANOL DAUN SINGAWALANG (Petiveria alliaceae) TERHADAP Mycobacterium tuberculosis STRAIN H37 RV PENELITIAN EKSPERIMENTAL LABORATORIS. Thesis thesis, UNIVERSITAS AIRLANGGA.

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Abstract

Mycobacterium tuberculosis is the causative agent of tuberculosis. This study aims to determine the minimum dose of ethanol leaf extract singawalang (Petiveria alliaceae) that can inhibit the growth of Mycobacterium tuberculosis strain H37RV, and to know whether there is a dose effect of the ethanol extract of the leaves and the growth of bacterial colonies singawalang Mycobacterium tuberculosis strain H37RV. Bacteria testing of Mycobacterium tuberculosis strains H37Rv and implementation of research conducted in the LPT (Institute for Tropical Diseases) Airlangga University for 8 weeks of incubation. Testing activities performed by growing the bacteria Mycobacterium tuberculosis strain H37RV test in Middlebrook 7H10 medium containing ethanol leaf extract in different doses singawalang ( 0.25 mg / ml, 0.5 mg / ml, 1 mg / ml, 2 mg / ml, 4 mg / ml; 8 mg / ml 16 mg / ml). The number of colony growth of Mycobacterium tuberculosis strain H37 RV ever present in the positive control treatment and no growth of colonies of bacteria Mycobacterium tuberculosis strain H37 RV to treatment with the ethanol extract of leaves singawalang in doses of 2 mg / ml and above this study is expected to provide scientific information that singawalang leaf ethanol extract at a dose of 2 mg / ml was able to inhibit the growth of colonies of Mycobacterium tuberculosis H37 RV strain.

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