TREES, 090810663M (2010) PERBEDAAN KADAR CRP DAN KADAR IgA ANAK BALITA GIZI KURANG BERDASARKAN KADAR SENG DI WILAYAH KERJA PUSKESMAS PENELEH KECAMATAN GENTENG KOTA SURABAYA. Thesis thesis, UNIVERSITAS AIRLANGGA.

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Abstract

The effect of zinc deficiency may have negative influence on immune response that takes place during the critical growth period. Disordered immune system may lead to the increased risk of infectious diseases. Immunoglobulin A (IgA) has a function as the first barrier against microorganisms and cell proliferation within immune system, which is also highly influenced by zinc. In children with malnutrition, including zinc, disorder, the production of secretory IgA in their digestive system is also disturbed. The objective of this study was to analyze the difference of zinc-based CRP and IgA levels in underfives with undernutrition at the working area of Community Health Center, Peneleh, Surabaya. The study was an analytic observational, and the design was comparative study with cross-sectional data collection. This sub-population comprised 101 infants, and the result of serum zinc levels were normal (>13.00 pmol/L) and abnormal (<13.00 µmol/L). Sampling was done using simple random sampling, with sample size of 28 underfives with undernutrition grouped into two groups, 14 underfives with normal zinc level and 14 underfives with abnormal zinc level. Collected data were processed manually using computer, and then the data were tabulated, analyzed statistically with descriptive statistics and Chi-Square analysis for data with nominal scale, Mann Whitney for data with ordinal scale, and independent T test for data with interval/ratio scale with difference significance level of p < 0.05. Result showed no significant (p > 0.05) in underfives' characteristics (age and sex), and family characteristics (occupation, education, income, expense for food, number of family members, mothers' level of knowledge), nutrient consumption pattern (energy, carbohydrate, protein, fat. and zinc) in underfives with undernutrition based on zinc level. There was no difference (p > 0.05) in food taboo, environmental sanitation, housing and self-hygiene, and illness frequency in underfives with undernutrition based on vinC level The results of study using Chi-Square statistical analysis showed no difference between CRP level in underfives with undernutrition based on zinc with p = 1.000 and the result of independent two-sample T test showed significant difference between IgA level in underfives with undernutrition based on zinc with p = 0.005. It is suggested in this study to provide nutrient dense foods such as shredded oyster or oyster-rich snack content, also considering the consumption of vegetables and fruits that are low in children under five with undernutrition, it is necessary to make alternative processing of vegetables and fruit as koyur .

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