Ardiani Dwi Pramesti, 061211133003
(2016)
EFEK FITO PROTEKTIF EKSTRAK BATANG PISANG
AMBON (Musa paradisiaca var. Sapientum) TERHADAP
GAMBARAN HISTOPATOLOGI DUODENUM TIKUS
PUTIH (Rattus norvegicus) YANG DIINDUKSI
INDOMETASIN.
Skripsi thesis, Universitas Airlangga.
Abstract
Indomethacin is Non-Steroidal Anti Inflammatory Drug (NSAID) such as fever,
rheumathoid arthritis treatment and post surgery treatment. In this reasearch, 15
mg/kg BB indomethacin was given orally. Indomethacin has side effect on
duodenum which is caused Inflammatory. The flavonoid in ethanol extract of
ambon banana stem (Musa paradisiaca var.sapientum) had possibility to be
used as a preventive. This research was aimed to determine the histopatology of
duodenum rats. This experiment used male rats (Rattus norvegicus) aged 8-12
weeks and weigh 150 grams, were divided into five experimental groups, those
were control-rats, Indomethacin induced rats, and group of ambon banana stem
extract with dose of P1 = 20 mg/150gBW, P2 = 40 mg/150gBW, P3 = 80
mg/150gBW. Each duodenum specimen was processed and histopathological
changes were observed. Score of epithelial integrity as qualitative data were
analyzed with Kruskall Wallis test continued by Z test.The result of the study
showed that ethanol extract of ambon banana stem could repaired damage of
duodenum histopathology (p<0,05). Duodenum histopathology repaired was
marked by improvements epithelial cells of duodenum.
| Item Type: |
Thesis
(Skripsi)
|
| Additional Information: |
KKC KK KH 65-16 Pra e |
| Uncontrolled Keywords: |
Inflammatory, Indomethacin, ambon banana stem (Musa paradisiaca
var.sapientum) , histopathology duodenum |
| Subjects: |
S Agriculture > SF Animal culture > SF600-1100 Veterinary medicine > Including veterinary genetics, ethology, anatomy, physiology, embryology, pathology |
| Divisions: |
06. Fakultas Kedokteran Hewan |
| Creators: |
| Creators | NIM |
|---|
| Ardiani Dwi Pramesti, 061211133003 | UNSPECIFIED |
|
| Contributors: |
| Contribution | Name | NIDN / NIDK |
|---|
| Thesis advisor | Rochmah Kurnijasanti, Dr. ,drh., M.Si. | UNSPECIFIED | | Thesis advisor | Ismudiono, drh., M.S., Prof. Dr. | UNSPECIFIED |
|
| Depositing User: |
sukartini sukartini
|
| Date Deposited: |
01 Mar 2017 20:29 |
| Last Modified: |
20 Jun 2017 16:28 |
| URI: |
http://repository.unair.ac.id/id/eprint/53769 |
| Sosial Share: |
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