UJI AKTIVITAS MUSCLE RELAXANT DARI FRAKSI MINYAK KENCUR (Kaempferia galanga L.) DENGAN METODE ROTAROD

ODE ABDUL MAJID AL IDRUS, 05111196 (2016) UJI AKTIVITAS MUSCLE RELAXANT DARI FRAKSI MINYAK KENCUR (Kaempferia galanga L.) DENGAN METODE ROTAROD. Skripsi thesis, Universitas Airlangga.

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Abstract

This research aimed to determining the potential of oil fraction rhizome (Kaempferia galangal L) as muscle relaxant on skeletal muscle of mice. Mice were divided into 5 groups : positive control, three test group with different dosage levels, and negative control groups. For the negative control group used CMC-Na with levels of 5 % . For the test group used a dose of 1 kencur oil fraction with a dose of 4.02 mg / 20 g BB mice , 8.04 mg / 20 g BB mice to doses of 2 , and 16.09 mg / 20 g BB mice to doses of 3, while for Diazepam is used positive control group at a dose of 0.5408 mg / 20 g BB mice. From the Post Hoc LSD test results can be seen that there are significant differences between negative control group to test group dose of 1, 2 and 3 are marked with significance values less than 0.05. On test group dose 3 to positive control showing significance value of 0.066 (p> 0.05), which showed no significant difference. This showed a dose of 3 (oil fractions kencur 16.09 mg / 20 g BB of mice) has a potential that is almost comparable to the positive control (diazepam 0.5408 mg / 20 g BB of mice) in a muscle relaxant activity. Keywords : Kaempferia galanga L ,myalgia, muscle relaxant, rotarod

Item Type: Thesis (Skripsi)
Additional Information: KKB KK-2 FF.FT. 33-16 Idr u
Uncontrolled Keywords: Kaempferia galanga L ,myalgia, muscle relaxant, rotarod
Subjects: R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica
Divisions: 05. Fakultas Farmasi > Farmakognosi Fitokimia
Creators:
CreatorsNIM
ODE ABDUL MAJID AL IDRUS, 05111196UNSPECIFIED
Contributors:
ContributionNameNIDN / NIDK
Thesis advisorHerra Studiawan, Drs., MS., AptUNSPECIFIED
Thesis advisorLusiana Arifianti, S.Farm., M.Farm., Apt.UNSPECIFIED
Depositing User: Tatik Poedjijarti
Date Deposited: 02 Apr 2017 23:07
Last Modified: 02 Apr 2017 23:07
URI: http://repository.unair.ac.id/id/eprint/55701
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