MAZAYA RAMADHANI NADHILA PUTRI, 061011209 (2016) POTENSI EKSTRAK DAUN KAMBOJA ( Plumeria acuminata) TERHADAP JUMLAH ANGIOGENESIS DAN SEL PMN PADA LUKA INSISI MENCIT (Mus musculus). Skripsi thesis, Universitas Airlangga.

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Abstract

This research was conducted to verify the potential of Kamboja leaves (Plumeria acuminata), as a medicinal plant for wound healing incision on mice. Twenty of two-three months old male mice with 25 g average body weight was divided into five treatment groups, a negative control (P0) was given CMC Na, positive control (P1) was given Povidone iodine 10%, P2, P3, P4 was given concentration 15%, 20%, 25% of kamboja leaves extract that given topically at two time a day respectively. Data was obtained by microscopic observation of the wound skin, based on semiquantitative data scoring including angiogenesis, and inflammatory cells (PMN). The data were statistically analyzed by Kruskal-Wallis to be continued with Mann-Whitney test. The result showed that there is no were significant different (p<0,05) between treatment groups of inflammatory cells (PMN) and angiogenesis.

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