VIVI HARDIANTY HARUN, 061211131060 (2016) EFEKTIVITAS IGY ANTI NEURAMINIDASE VIRUS AI CLADE 2.1 DALAM MENGHAMBAT PERTUMBUHAN VIRUS AI CLADE 2.3 PADA TELUR AYAM BEREMBRIO. Skripsi thesis, Universitas Airlangga.

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Abstract

The aim of this study was to know the effectiveness of anti NA IgY of clade 2.1 to inhibit clade 2.3 of Avian Influenza (AI) virus. This experimental method using a Completely Randomized Design (CRD) with a 5x5 factorial pattern, so there are 25 combination groups and its repeated 3 times. There were two factors that has been used; anti NA IgY of clade 2.1 doses (0, 50, 100, 200 and 400 μg/μl) and virus titre of clade 2.3 AI viruses (0, 1, 10, 100 and 1000 EID50). Inhibition effects of anti NA IgY of clade 2.1 to the clade 2.3 Avian Influenza (AI) virus was quantified by Indirect ELISA assay. OD values was analyzed by ANOVA and Duncan Test. The results showed that the effectivenessof anti NA IgY of clade 2.1 doses significantly different (p<0.01). In conclusion, anti NA IgY of clade 2.1 AI viruses has the effectiveness to inhibit the growth of clade 2.3 AI virus. Dose of 200μg/μl and 400 μg/μl was the most optimal dose than another doses.

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