Soemantri, Djoko and Johanes Nugroho (2012) Hubungan Antara Ketebalan Intima Media Arteri Karotis (CIMT) dan Tekanan Sistolik Tungkai Lengan (ABI) pada Penderita dengan Faktor Risiko Penyakit Jantung Koroner Asimtomatis di Poloklinik Jantung RSUD Dr. Soetomo Surabaya. Project Report. Pusat Penelitian dan Pengabdian Kepada Masyarakat, Universitas Airlangga.

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Abstract

We studied associations between ankle-brachial index (ABI) and subclinical atherosclerosis using CIMT. Participats comparose 36 patients include 25 women (69,4%) and 11 men (30,6%) with an averadge age 59,4±5,26 years who were asymptimatic and free of clinically eveident cardiovascular disease and have at least 2 risk factors of CVD. Measurements included ankle-brachial index (ABI), mean and maximum carotid intima-media thickness (CIMT) of common carotid artery, and cardiovascular risk factors that consist of age, hypertension, diabetes, smoking, dyslipidemia, and family history of premature CAD. ABI categories were defined : <0.90 (abdnormal ABI or definite pepheral arterial disease (PAD)), 0.90-0.99 (borderline ABI), and 1.00-1.40 (normal ABI). Significantly higher common carotid artery intima-media thickness in both of mean and maximum CIMT were observed in patients with definite PAD and borderline ABI compared with that inpatients with normal ABI (p<0,05). Analysis showed significantly weak correlation between mean CIMT and ABI (p=0,024; r=-0,376); and between maximum CIMT and ABI (p=0,039; r=-0,345). This study provide evidence that atherosclerosis process of the lower extremities arteries associated with subclinical atherosclerosis as reflected by increasing of CIMT of common carotid artery. This study also indicate patients with abnormal and borderline ABI have significantly greater degree of subclinical atherosclerosis and may imply increased risk of cardiovascular events

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