MERYNDA MEGA KUSUMA, 061311133005 (2017) EFEKTIVITAS GEL EKSTRAK DAUN BINAHONG (Anredera cordifolia (Ten.) Steenis) TERHADAP PENURUNAN JUMLAH SEL PMN PADA PROSES PENYEMBUHAN LUKA INSISI MENCIT (Mus musculus) JANTAN. Skripsi thesis, Universitas Airlangga.

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Abstract

The purpose of this study was to learn about the effectivenesss of binahong leaves gel extract to reduce the number of PMN cells in incision wound healing process of male mice (Mus musculus). Twenty male mice (Mus musculus) were divided into four groups i.e P0 (HPMC 3%), P1 (Povidone iodine), P2 (binahong leaves gel extract with 10% concentration) and P3 (binahong leaves gel extract with 20% concentration). All of treatment was done for three days (72 hours). Histopathological examination was done and data analysis used ANOVA followed with Duncan test. The analysis showed there was significant difference between P0 with P1, P2 and P3 (p<0.05), that P0 has mean and standard deviation 357.8 ± 75.98, P1 128.6 ± 11.3, P2 112.4 ± 11.63 and P3 70.6 ± 7.23. The results showed that P0 has significant difference with P1, P2 and P3, P1 insignificance different with P2 but significant difference with P3, and P2 insignificance different with P3. The conclusion of this study was binahong leaves gel extract can reduce the number of PMN cells in incision wound healing of male mice (Mus musculus), the best result in this study to reduce the number of PMN cells was binahong leaves gel extract with 20% concentration.

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