Deorina Roully Gratia Siregar, NIM011411133016 (2017) UJI EFEK ANTIMIKROBA DAUN ALPUKAT (Persea americana) TERHADAP Streptococcus pyogenes. Skripsi thesis, Universitas Airlangga.

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Abstract

Introduction: Streptococcus pyogenes is a common bacteria in development country. This bacteria could easily transferred by droplet and the patient could becarrier. Streptococcus pyogenes also could lead to some complication, such as scarlet fever, rheumatic fever, and acute glomerulonephritis. Medication against this bacteria is antibiotic such as penicillin and erythromicin, but now a day the resistance of penicillin and erythromicin are increase. Due to their virulency and resistancy, we wanted to have new antibacterial drug against Streptococcus pyogenes. We hoped Avocado Leaves (Persea americana) that evidently had antibacterial activity in Bacillus subtilis, Escherichia coli, Salmonella typhi, Staphylococcus aureus, Pseudomonas aeruginosa, and Candida albicans, could also inhibited and killed Streptococcus pyogenes. Methods: Is an experimental laboratory ressearch, tested in vitro using dilution metod Results: MIC (Minimum Inhibitory Concentration) in this research couldn’t be measure because of the color of the exctract. MBC (Minimum Bactericidal Concentration) from exctract Persea americana against Streptococcus pyogenes is 357 mg/ml. No colony grew in plate K1, T1, and T2. There was 283 in T3 and 11.204 in T4.

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