REZA DEVIA LARASATI (2015) Pola Penggunaan Obat Anti Tuberkulosis (Oat) Pada Pasien Spondilitis Tuberkulosis Di Rsud Dr. Soetomo Surabaya (Smf Ortopedi Dan Traumatologi). Skripsi thesis, UNIVERSITAS AIRLANGGA.
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Abstract
Background : Spondylitis Tuberculosis is Mycobacterium tuberculosis infection of the spine, its clinical course is relatively indolent. Patient frequently diagnosed at late phase with kyphosis and neurological deficit. Oral anti tuberculosis agents are treatment of choice at early phase and surgery is reserved for advanced cases with various techniques. Objective : The aims of this study were to analyze the profile of antituberculosis drugs used in spondylitis tuberculosis, and to identify drug related problem (DRPs) of antituberculosis drug. Result : The result showed that from 13 spondylitis tuberculosis patients, the majority were female (54%) with the age of 20-25 years old (31%). The most common symptoms that occured were back pain (46%). Drug related problems that found in the study were adverse drug reaction like nausea, vomiting, cosnstipation, and antituberculosis interaction with an other therapy, paracetamol and antacid. Conclution : Antituberculosis drug use in spondylitis TB were isoniazid, rifampisin,pyrazinamide, and ethambutol in combination and streptomycin was administered with intramuscular route. They were administered once daily orally or administered with fix dose combination third daily orally.The other therapy was advance in the surgical management for decrease kyphotic deformity of spine.
Item Type: | Thesis (Skripsi) | |||||||||
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Additional Information: | KKB KK-2 FF.FK. 01-18 Lar p | |||||||||
Uncontrolled Keywords: | Spondylitis tuberculosis, Tuberculosis of spine, antituberculosis drugs, isoniazid, pyrazinamide, ethambutol, streptomycin | |||||||||
Subjects: | R Medicine > RM Therapeutics. Pharmacology > RM300-666 Drugs and their actions | |||||||||
Divisions: | 05. Fakultas Farmasi > Farmasi Klinis | |||||||||
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Depositing User: | Tatik Poedjijarti | |||||||||
Date Deposited: | 15 Apr 2018 22:53 | |||||||||
Last Modified: | 27 Mar 2020 05:29 | |||||||||
URI: | http://repository.unair.ac.id/id/eprint/71834 | |||||||||
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