Airlanggins A-B, two new isoprenylated benzofuran-3-ones from the stem bark of Calophyllum soulattri

Tanjung, Mulyadi and Fida Rachmadiarti and Prameswari, Anindita and Wustha Agyani, Villa Ultha and Saputri, Ratih Dewi and Tjahjandarie, Tjitjik Srie and Syah, Yana Maolana (2017) Airlanggins A-B, two new isoprenylated benzofuran-3-ones from the stem bark of Calophyllum soulattri. Natural Product Research, 32 (13). pp. 1493-1498. ISSN 1478-6419

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Official URL: https://doi.org/10.1080/14786419.2017.1380027

Abstract

ABSTRACT Two new isoprenylated benzofuran 3-ones, airlanggin A (1) and B (2) along with two known xanthones, ananixanthone (3) and trapezifolixanthone (4) were isolated from the stem bark of Calophyllum soulattri. Structures of all the compounds were elucidated using extensive spectroscopic methods, including UV, IR, HRESIMS, 1D and 2D NMR. Compounds 1–4 were evaluated for their cytotoxicity against P-388 cells, showing that compound 3 was the most active with IC50 0.68 μg/mL and compound 1 showed moderate activity with IC50 5.80 μg/mL.

Item Type: Article
Uncontrolled Keywords: Airlanggins A and B; isoprenylated benzofuran- 3-one; Calophyllum soulattri; P-388 cell
Subjects: Q Science > QD Chemistry
Divisions: 08. Fakultas Sains dan Teknologi > Kimia
Creators:
CreatorsNIM
Tanjung, MulyadiUNSPECIFIED
Fida RachmadiartiUNSPECIFIED
Prameswari, AninditaUNSPECIFIED
Wustha Agyani, Villa UlthaUNSPECIFIED
Saputri, Ratih DewiUNSPECIFIED
Tjahjandarie, Tjitjik SrieUNSPECIFIED
Syah, Yana MaolanaUNSPECIFIED
Depositing User: Mr Akhmad Nurfizal Reza
Date Deposited: 02 Mar 2022 02:24
Last Modified: 02 Mar 2022 02:24
URI: http://repository.unair.ac.id/id/eprint/73031
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