Krista Devi P, Ivan and Arundina,, lra and Istiati, Istiati (2014) Potensi Anti jamur Ekstrak Bunga Kembang Sepatu Terhadap Candida albicans (Antifungal potentiality of Hibiscus rosa-sinensis, L. flower) extract against Candida albicans. Jurnal Kedokteran Gigi Denta, 8 (2). ISSN 1907-5987

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Abstract

Background: C. albicans can cause health problems in the oral cavity tissue. Therefore require antifungal treatment. However, treatment with antifungal drug has side effects. Hibiscus rosa-sinensis L. flower contain cyanidin and quercetin that have been reported to have antifungal activity against various fungal pathogens. By the study that have been done, the concentration of 40% was not give significant result. So in this study was the concentration increased to 100%, 87.5%, 75%, 62.5%, 50%, for significant result. Purpose: The aim of this study was to know the antifungal potentiality of Hibiscus rosa-sinensis L. flower extract with a concentration of 100%, 87.5%, 75%, 62.5%, 50% against C. albicans. Materials and Methods: For each 25 grams of powdered dried flowers that have been placed in 100 ml of methanol to get pure extract evapourator without solvent. This research using multiple depletion to get a concentration of 50%, 62.5%, 75%, 87.5%, 100%. To ensure the growth of C. albicans, is done by culturing on Sabouraud Dextrose Agar medium. Result: There were significant difference between positive control and a concentration of 50%, 62.5%. Conclusion: There are differences inhibitory effect of Hibiscus rosa-sinensis L. flower extract against C. albicans and MIC at 75%.

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