Esti Hendradi and Dewi Melani Hariyadi and Muhammad Faris Adrianto (2016) Activity of Cyprofloxacine from implant with cross link agent genipin in composites to Staphilococcus aureus ATCC25923 dan Escherichia coli ATCC 25922. In: Proceeding The 4th Current Drug Development International Conference (CDD 2016). Faculty of Pharmaceutical Sciences, Princes of Songkla University, Songkhla, pp. 188-189. ISBN 978-616-271-303-3

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Abstract

The Research on effectiveness of cyprofloxacin against Staphylococcus aureus ATCC25923 and Escherichia coli NICC 25922bacteria was done. Composite mixture used was Bovine Hydroxyapatite-Chitosan which cross link with genipin as the carrier Ciprofloxacin. The ratio between Ciprofloxacin: BHA: Chitosan: l0:30:60. As Cross linker was genipin 0.7o ,the concentration of Ciprofloxacin as active ingredient was 10%. The results showed that the implant can release preparation Cyprofloxacin by sustained released system in vitro and to inhibit bacterial growth Staphilococcus aureus ATCC25923 and also Escherichia coli ATCC 25922.

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