ROHANA MERITHA, 061511133122 (2019) DAYA ANTHELMINTIKA EKSTRAK ETANOL BUAH PARE (Momordica charantia L.) TERHADAP CACING Fasciola gigantica SECARA IN VITRO. Skripsi thesis, Universitas Airlangga.

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Abstract

The aims of this study was to know the Anthelmintic Activity of Ethanol Extract of Bitter Melon Fruit (Momordica charantia L.) Against F. gigantica worm in vitro. Method that used in the research was completely randomized design. There were six treatments and each treatment was done in four replications. This research used ten F. gigantica in each treatment for all replication. The observation and recording of dead F. gigantica was done at 2, 4, 6, 8, 10 hours. Fasciola gigantica were declared dead if there was no movement when disturbed by anatomy tweezers and when dipped in slightly warm water (50℃). The obtained data was analyzed using ANOVA factorial and continued with Duncan Multiple Range Test. The result of this research showed the most effective concentration of Momordica charantia L. Ethanol extract was 10%, the higher concentration of the extract, the higher property of its anthelmintic. Probit analysis was used to calculate the LC50 and LC90. The results were LC50 of Momordica charantia L. extract was 5.22% at 2 hours, 2.6% at 4 hours, 1.52% at 6 hours, 1.06% at 8 hours, 0.64% at 10 hours and the LC90 was 1,71% at 10 hours.

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