BAGUS ADITYA KUSWARDHANA, 061411133010 (2019) POTENSI ANTIOKSIDAN EKSTRAK KULIT BUAH NAGA MERAH (Hylocereus polyrhizus) TERHADAP MOTILITAS, VIABILITAS, DAN KEUTUHAN MEMBRAN PLASMA SPERMATOZOA MENCIT (Mus musculus) DENGAN PAPARAN SUHU PANAS. Skripsi thesis, Universitas Airlangga.

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Abstract

This research aims to determined the antioxidant potential of Red Dragon fruit (Hylocereus polyrhizus) skin extract against motility, viability and integrity plasma membranes spermatozoa of mice (Mus musculus) after being exposed to hot temperature. The polyphenol in the red dragon fruit skin serves an antioxidant counteracting free radicals. A total of 20 mices (Mus musculus) were used in this study with an average age of 2 months. The study was divided into five treatments and four replications, consisting of: K(-) as negative control given CMC Na 1% as much as 0.5 ml, K(+) as positive control was exposed to 40° C for 45 minutes and CMC Na 1% of 0.5 ml. P1, P2 and P3 are exposed to 40° C for 45 minutes and red dragon fruit skin extract with a multilevel dose of P1: 250 mg/kgBB, P2: 500 mg/kgBB, and P3: 1000 mg/kgBB that each dose was dissolved in CMC Na 1% of 0.5 ml. The results showed that red dragon fruit skin extract to the mice maintain the motility, viability, and integrity of plasma membrane. The good result was shown by P3 group given a dose of 1000 mg/kgBB.

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