VALIDASI METODE PENETAPAN KADAR SODIUM LAURIL SULFAT DALAM SEDIAAN TABLET SECARA SPEKTROFOTOMETRI UV-VIS

SALMAN SALIM, 051311133144 (2019) VALIDASI METODE PENETAPAN KADAR SODIUM LAURIL SULFAT DALAM SEDIAAN TABLET SECARA SPEKTROFOTOMETRI UV-VIS. Skripsi thesis, Universitas Airlangga.

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Abstract

Simple, accurate and precise UV-Vis spectrophotometric method was validated for the determination of sodium lauryl sulfate (SLS) in tablet. The method based on the formation of chloroform extractable colored compound. The colored compound is the result of ion pairing complex between SLS with 0.005% methylene blue in phosphate buffer of pH 7.2. Showing the maximum absorption of the complex substance at 652 nm. The proposed method showed good linearity (r2 = 0.9969) in the range concentration of 2 ppm to 10 ppm. The precision was less than 5%, while accuracy of SLS was (98.59 ± 1,26) %. The proposed method is robust in pH variation of 0.2.

Item Type: Thesis (Skripsi)
Additional Information: KKB KK FF KF 03/19 Sal v
Uncontrolled Keywords: Sodium Lauryl Sulfate, UV-Vis Spectrophotometry, Method Validation
Subjects: R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica
Divisions: 05. Fakultas Farmasi > Kimia Farmasi
Creators:
CreatorsNIM
SALMAN SALIM, 051311133144UNSPECIFIED
Contributors:
ContributionNameNIDN / NIDK
Thesis advisorM. Yuwono., Prof. Dr. rer. nat. H. , M.S., AptUNSPECIFIED
Depositing User: Unnamed user with email indah.fatma@staf.unair.ac.id
Date Deposited: 24 Apr 2019 08:20
Last Modified: 24 Apr 2019 08:20
URI: http://repository.unair.ac.id/id/eprint/81982
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