SAYYIDATI ARISTIFANNIY ROHIM, 091615053001 (2019) SINTESIS DAN KARAKTERISASI CARBON DOTS BERBAHAN DASAR ASAM ASKORBAT SEBAGAI KANDIDAT PENANDA BIOLOGIS KANKER. Thesis thesis, Universitas Airlangga.
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Abstract
This study aimed to synthesize and characterize of carbon dots (CDs) originating from ascorbic acid as biomedical applications. This material could be used for a cancer biomarker. The synthesis used microwave radiation as heating source with time variations. The results showed that the best sample had ± 2 nm and the highest fluorescence intensity which was microwave-irradiated for 3.30 minutes. This sample was conjugated with folic acid (FA) which had functional groups that indicated CDs and folic acid. The result of the cytotoxicity test showed non-toxic doses were 0.6 μM CDs; 0.6 and 6 μM CDs – FA. The best dose was used to cell targeting imaging to bladder cancer cell – line. The explanations about characterizations would be discussed on discussion chapter.
| Item Type: | Thesis (Thesis) | |||||||||
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| Additional Information: | KKC KK TT. 05-19 Roh s | |||||||||
| Uncontrolled Keywords: | carbon dots (CDs), ascorbic acid, folic acid, microwave, cancer biomarker | |||||||||
| Subjects: | R Medicine > R Medicine (General) > R856-857 Biomedical engineering. Electronics. Instrumentation | |||||||||
| Divisions: | 09. Sekolah Pasca Sarjana | |||||||||
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| Depositing User: | Tatik Poedjijarti | |||||||||
| Date Deposited: | 26 Apr 2019 08:07 | |||||||||
| Last Modified: | 26 Apr 2019 08:07 | |||||||||
| URI: | http://repository.unair.ac.id/id/eprint/82055 | |||||||||
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