Sri Kunarti and Agus Subiwahjudi and Ratna Dewi and Tamara Yuanita (2017) Comparison of IPMP, Chlorine Dioxide and Chlorhexidine Gluconat Contained in Mouthwashes for Reducing Exopolysaccharide on Streptococcus Mutans Biofilms. In: Proceeding International Medical Device and Technology Conference (IMEDITEC) 2017. Universiti Technologi Malaysia, Johor. ISBN 978-967-0194-93-6 FBME

	Text (PEER REVIEW 1) Tamara per 13.pdf Download (423kB)
	Text (SIMILARITY) Comparison of IPMP, Chlorine Dioxide and Chlorhexidine Gluconat Contained in Mouthwashes for Reducing Exopolysaccharide on Streptococcus Mutans Biofilms.pdf Download (1MB)
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Abstract

Background: Streptococcus mutans is the main bacteria forming biofilms associated with dental carious lesions. S. Mutans utilizes dietary carbohydrates to rapidly synthesize exopolysaccharides (EPS) using glucosyltransferase and fructosyltransferase enzyme. Purpose: This research aimed to assess the effects of three active ingredients of mouthwashes on EPS formed on S.mutans biofilms and to determine which ingredient is the most effective in reducing EPS. Method: This research is an experimental laboratory study with post test only control group design using EPS formed on Streptococcus mutans biofilms. EPS then was fluorescently labelled using alexa fluor 647 dextran conjugate stain and analyzed using Confocal Laser Scanning Microscopy and Fluoview ver 1.7a Software. Results: There is a significant difference between those three active ingredients of mouthwashes in reducing EPS and IPMP significantly eliminates EPS. Conclusion. IPMP has the most potential in eleminating EPS formed on Streptococcus mutans biofilms compared to other active ingredients.

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