Sugiyartono and Tutiek Purwanti and Isnaeni and Dhenok Reso Fenda Asega (2014) Influence of Emcompress Concentration on the Physical Properties of Tablet containing Lactobacillus spp. and Guava Leaves Extract. Asian Journal of Pharmaceutical Research, 4 (4). pp. 189-194. ISSN 2231–5683

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Abstract

Emcompress are widely used in tablet formulation because it has good compressibility. The objective of this research is to investigate the influence of emcompress concentration on the physical properties of tablet containing Lactobacillus spp. and guava leaves extract. Tablets containing Lactobacillus spp. and guava leaves extract prepared into four series and compressed by direct compression method using emcompress as a filler. Each formula using emcompress with different concentration i.e.: 0% (F1), 0,1% (F2), 0,19% (F3) and 0, 5% (F4). All tablet met the pharmacopoeia requirements during following test:hardness and friability. The disintegration time and moisture contents did not meet the pharmacopoeia requirements. Conclusion of this research is: increasing the concentration of emcompress will increase the tablet’s hardness and decrease the tablet’s friability but did not influence other physical properties of tablet containing Lactobacillus spp. and guava leaves extract.

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